3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
- Product Name
- 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
- CAS No.
- 71997-32-5
- Chemical Name
- 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
- Synonyms
- Cordycepin 5′-triphosphate;Cordycepin-5''-triphosphoric acid;3'-deoxyadenosine 5'-triphosphate;cordycepin 5'-triphosphate sodium;CORDYCEPIN 5'-TRIPHOSPHATE SODIUM SALT;3'-deoxyadenosine-5'-triphosphate sodium;Cordycepin 5'-triphosphate sodium salt >=95%;3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT;Sodium (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-3-olate
- CBNumber
- CB2186438
- Molecular Formula
- C10H17N5NaO12P3
- Formula Weight
- 515.18
- MOL File
- 71997-32-5.mol
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Property
- storage temp.
- -20°C
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/22-36/37/38-40
- Safety Statements
- 22-26-36-45
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- C9137
- Product name
- Cordycepin 5′-triphosphate sodium salt
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $189
- Updated
- 2024/03/01
- Product number
- C9137
- Product name
- Cordycepin 5′-triphosphate sodium salt
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $773
- Updated
- 2024/03/01
- Product number
- NUC0003767
- Product name
- CORDYCEPIN-5'-TRIPHOSPHATE SODIUM SALT
- Purity
- 97.00%
- Packaging
- 10MG
- Price
- $1663.2
- Updated
- 2021/12/16
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Chemical Properties,Usage,Production
Uses
Cordycepin 5′-triphosphate sodium salt has been used:
- as a transcriptional inhibitor in RNA decay assay
- to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
- as a positive control in in vitro assays for polymerase inhibition
- as a precursor to produce cordycepin monophosphate
Definition
ChEBI: Cordycepin triphosphate is a purine ribonucleoside 5'-triphosphate. It has a role as an antimetabolite, an antifungal agent, an antineoplastic agent and an antiviral agent. It is functionally related to a cordycepin.
General Description
Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.
Biochem/physiol Actions
Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.